临床专家
张琳
职称：主任技师
专长
胃癌和食管癌的消化道肿瘤的转化医学
一、基本情况
主任技师、硕士生导师，肿瘤学博士。
二、学习及工作经历
2001.09 - 2006.07 南华大学医学院临床检验系
2010.09 - 2012.12 中山大学基础医学免疫学，硕士
2014.09 - 2017.06 中山大学肿瘤防治中心肿瘤学，博士
2006.04 - 2012.12 中山大学肿瘤防治中心检验科，技师
2013.01 - 2017.12 中山大学肿瘤防治中心检验科，主管技师
2018.01 – 2022.12 中山大学肿瘤防治中心检验科，副主任技师
2023.01 – 至今 中山大学肿瘤防治中心检验科，主任技师
2010.09 - 2012.12 中山大学基础医学免疫学，硕士
2014.09 - 2017.06 中山大学肿瘤防治中心肿瘤学，博士
2006.04 - 2012.12 中山大学肿瘤防治中心检验科，技师
2013.01 - 2017.12 中山大学肿瘤防治中心检验科，主管技师
2018.01 – 2022.12 中山大学肿瘤防治中心检验科，副主任技师
2023.01 – 至今 中山大学肿瘤防治中心检验科，主任技师
三、主持科研项目
主要研究食管癌和胃癌的消化道肿瘤的转化医学。主持国家自然科学基金、广东省自然科学基金项目及广东省食管癌研究所科技计划各1项。
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一、基本情况
肿瘤学博士，主任技师。
二、学习及工作经历
2001.09 - 2006.07 南华大学医学院临床检验系
2010.09 - 2012.12 中山大学基础医学免疫学，硕士
2014.09 - 2017.06 中山大学肿瘤防治中心肿瘤学，博士
2006.04 - 2012.12 中山大学肿瘤防治中心检验科，技师
2013.01 - 2017.12 中山大学肿瘤防治中心检验科，主管技师
2018.01 – 2022.12 中山大学肿瘤防治中心检验科，副主任技师
2023.01 – 至今 中山大学肿瘤防治中心检验科，主任技师
2010.09 - 2012.12 中山大学基础医学免疫学，硕士
2014.09 - 2017.06 中山大学肿瘤防治中心肿瘤学，博士
2006.04 - 2012.12 中山大学肿瘤防治中心检验科，技师
2013.01 - 2017.12 中山大学肿瘤防治中心检验科，主管技师
2018.01 – 2022.12 中山大学肿瘤防治中心检验科，副主任技师
2023.01 – 至今 中山大学肿瘤防治中心检验科，主任技师
三、主持科研项目
主要研究食管癌和胃癌的消化道肿瘤的转化医学。主持国家自然科学基金、广东省自然科学基金项目及广东省食管癌研究所科技计划各1项。
四、学术论文
第一及或通讯作者发表高水平文章：
1. Li Baoxia#, Wang Hengbang#, Qiu Miaozhen ,Luo Qiuyun, Yi Hanjie, Yan Xianglei, Pan Wentao, Yuan Luping , Zhang Yuxin, Xu Jianhua, Zhang Lin*, Yang Dajun*. Novel smac mimetic APG-1387 elicits ovarian cancer cell killing through TNFalpha, Ripoptosome and autophagy mediated cell death pathway. Journal of Experimental ＆Clinical Cancer Research. J Exp Clin Cancer Res. 2018 Mar 12; 37(1):53.doi: 10.1186/s13046-018-0703-9.
2. Ye Shubiao#, Cheng Yikan#, Zhang Lin#, Zou Yifeng, Chen Ping, Deng Yanhong, Huang Yan, Peng Jianhong, Wu Xiaojian*, Lan Ping*. Association of mismatch repair status with survival and response to neoadjuvant chemo(radio)therapy in rectal cancer. NPJ Precis Oncol. 2020 Sep 7;4:26. doi: 10.1038/s41698-020-00132-5.
3. Ni Huanhe#, Zhang Lin#, Huang He, Da Shuqin*, Li Jiang*. Connecting METTL3 and intratumoral CD33+ cells in predicting clinical outcome in cervical cancer.J Transl Med. 2020 Oct 15;18(1):393. doi: 10.1186/s12967-020-02553-z.
4. He Yi#, Mao Minjie#, Shi Wenjuan, He Zhonglian, Zhang Lin*, Wang Xueping*. Development and Validation of a Prognostic Nomogram in Gastric cancer with Hepatitis B virus infection.J Transl Med. 2019 Mar 25; 17(1):98. doi: 10.1186/s12967-019-1841-3.
5. Luo Qiuyun#, Di Tian#, Chen Zhigang#, Peng Jianhong, Sun Jian, Xia Zengfei, Pan Wentao, Luo Fan, Lu Feiteng, Sun Yuting, Yang Liqiong, Zhang Lin*, Qiu Miaozhen*, Yang Dajun*. Novel prognostic model predicts overall survival in colon cancer based on RNA splicing regulation gene expression. Cancer Sci.2022 Oct;113(10):3330-3346. doi: 10.1111/cas.15480. Epub 2022 Aug 16.
6. Luo Qiuyun#, Di Tian#, Qiu Miaozhen#, Xia Zengfei, Du Yong, Lin Runduan, Yang Liqiong, Sun Yuting, Yang Dajun*, Sun Jian*, Zhang Lin*. High AKAP8L expression predicts poor prognosis in esophageal squamous cell carcinoma. Cancer Cell Int.2022 Feb 21;22(1):90. doi: 10.1186/s12935-022-02492-3.
7. Huang Hao#, Chen Yao#, Weng Xuezi, Li Sirou, Zhang Lin*, Chen Peisong*.Development and Validation of a Nomogram for Evaluating the Prognosis of Immunotherapy plus Antiangiogenic Therapy in Non-small Cell Lung Cancer.Cancer Cell Int.2022 Aug 21;22 (1):261. doi: 10.1186/s12935-022-02675-y.
8.Ou Guoping#, Xing Shan#, Li Jianpei, Zhang Lin*, Chen Shulin*. Circulating tumor cells: a valuable marker of poor prognosis for advanced nasopharyngeal carcinoma. Mol Med. 2019 Nov 15; 25(1):50. doi: 10.1186/s10020-019-0112-3.
9. Ye Shubiao#, Cheng Yikan#, Deng Ru#, Deng Yanhong, Li Peisi, Zhang Lin*, Lan Ping*. The Predictive Value of Estrogen Receptor 1 on Adjuvant Chemotherapy in Locally Advanced Colorectal Cancer: A Retrospective Analysis with Independent Validation and Its Potential Mechanism. Front Oncol. 2020 Mar 20;10:214.
10. Pan Wentao#, Zhou Suna#, Pan Mengxian#, Luo Qiuyun, Zhang Lin*, Yang Dajun*, Qiu Miaozhen*. Role of systemic treatment for advanced/metastatic gastric carcinoma in the third-line setting: A Bayesian network analysis.Front Oncol.2020 Apr 23;10:513.doi: 10.3389/fonc.2020.00513. eCollection 2020.
2. Ye Shubiao#, Cheng Yikan#, Zhang Lin#, Zou Yifeng, Chen Ping, Deng Yanhong, Huang Yan, Peng Jianhong, Wu Xiaojian*, Lan Ping*. Association of mismatch repair status with survival and response to neoadjuvant chemo(radio)therapy in rectal cancer. NPJ Precis Oncol. 2020 Sep 7;4:26. doi: 10.1038/s41698-020-00132-5.
3. Ni Huanhe#, Zhang Lin#, Huang He, Da Shuqin*, Li Jiang*. Connecting METTL3 and intratumoral CD33+ cells in predicting clinical outcome in cervical cancer.J Transl Med. 2020 Oct 15;18(1):393. doi: 10.1186/s12967-020-02553-z.
4. He Yi#, Mao Minjie#, Shi Wenjuan, He Zhonglian, Zhang Lin*, Wang Xueping*. Development and Validation of a Prognostic Nomogram in Gastric cancer with Hepatitis B virus infection.J Transl Med. 2019 Mar 25; 17(1):98. doi: 10.1186/s12967-019-1841-3.
5. Luo Qiuyun#, Di Tian#, Chen Zhigang#, Peng Jianhong, Sun Jian, Xia Zengfei, Pan Wentao, Luo Fan, Lu Feiteng, Sun Yuting, Yang Liqiong, Zhang Lin*, Qiu Miaozhen*, Yang Dajun*. Novel prognostic model predicts overall survival in colon cancer based on RNA splicing regulation gene expression. Cancer Sci.2022 Oct;113(10):3330-3346. doi: 10.1111/cas.15480. Epub 2022 Aug 16.
6. Luo Qiuyun#, Di Tian#, Qiu Miaozhen#, Xia Zengfei, Du Yong, Lin Runduan, Yang Liqiong, Sun Yuting, Yang Dajun*, Sun Jian*, Zhang Lin*. High AKAP8L expression predicts poor prognosis in esophageal squamous cell carcinoma. Cancer Cell Int.2022 Feb 21;22(1):90. doi: 10.1186/s12935-022-02492-3.
7. Huang Hao#, Chen Yao#, Weng Xuezi, Li Sirou, Zhang Lin*, Chen Peisong*.Development and Validation of a Nomogram for Evaluating the Prognosis of Immunotherapy plus Antiangiogenic Therapy in Non-small Cell Lung Cancer.Cancer Cell Int.2022 Aug 21;22 (1):261. doi: 10.1186/s12935-022-02675-y.
8.Ou Guoping#, Xing Shan#, Li Jianpei, Zhang Lin*, Chen Shulin*. Circulating tumor cells: a valuable marker of poor prognosis for advanced nasopharyngeal carcinoma. Mol Med. 2019 Nov 15; 25(1):50. doi: 10.1186/s10020-019-0112-3.
9. Ye Shubiao#, Cheng Yikan#, Deng Ru#, Deng Yanhong, Li Peisi, Zhang Lin*, Lan Ping*. The Predictive Value of Estrogen Receptor 1 on Adjuvant Chemotherapy in Locally Advanced Colorectal Cancer: A Retrospective Analysis with Independent Validation and Its Potential Mechanism. Front Oncol. 2020 Mar 20;10:214.
10. Pan Wentao#, Zhou Suna#, Pan Mengxian#, Luo Qiuyun, Zhang Lin*, Yang Dajun*, Qiu Miaozhen*. Role of systemic treatment for advanced/metastatic gastric carcinoma in the third-line setting: A Bayesian network analysis.Front Oncol.2020 Apr 23;10:513.doi: 10.3389/fonc.2020.00513. eCollection 2020.
更新日期：2023年7月5日
