临床专家

林俊忠
职称:医学博士,主任医师,硕士生导师
专长
结直肠癌和胃肠胰神经内分泌肿瘤的综合治疗,尤其擅长结直肠癌的微创手术
一、基本情况
职称:医学博士,主任医师,硕士生导师
专长:结直肠癌和胃肠胰神经内分泌肿瘤的综合治疗,尤其擅长结直肠癌的微创手术。
二、学习及工作经历
2000.09—2007.06 中山大学肿瘤医院 临床医学 七年制
2011.08—2014.06 中山大学肿瘤医院 肿瘤外科 博士研究生
2015.09—2016.09 美国德州大学MD Anderson癌症中心 访问学者
2007.08至今 中山大学肿瘤医院工作
2018.01—2018.06 普宁市人民医院副院长(挂职)
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2007年毕业于中山大学中山医学院临床七年制,2015.09-2016.09于美国德州大学MD Anderson癌症中心访问学习,2018.01-2018.06于普宁市人民医院挂职副院长。致力于结直肠癌和胃肠胰神经内分泌肿瘤的综合治疗,擅长结直肠癌微创手术,包括腹腔镜、机器人辅助手术和经肛内镜显微切除等,曾获华南腹腔镜手术比赛冠军。现任全国抗癌协会大肠癌专委会肝转移学组委员,广东省大肠癌专委会青年委员会委员,广东省医疗行业协会微创外科管理分会委员等。承担或参与13个国家或省部级课题,发表高水平论文15篇,总影响因子超过50分,参编4部专业著作。
一、发表的第一作者和通讯作者文章:
1.Zhao YJ, Sun WP, Peng JH, Deng YX, Fang YJ, Huang J, Zhang HZ, Wan DS, Lin JZ and Pan ZZ. Programmed death-ligand 1 expression correlates with diminished CD8+ T cell infiltration and predicts poor prognosis in anal squamous cell carcinoma patients. Cancer management and research. 2018; 10:1-11.
2.Zhao Y, Lin J, Peng J, Deng Y, Zhao R, Sui Q, Lu Z, Wan D and Pan Z. Hepatitis B Virus Infection Predicts Better Survival In Patients With Colorectal Liver-only Metastases Undergoing Liver Resection. Journal of Cancer. 2018; 9(9):1560-1567.
3.Qiu MZ, Pan WT, Lin JZ, Wang ZX, Pan ZZ, Wang FH, Yang DJ and Xu RH. Comparison of survival between right-sided and left-sided colon cancer in different situations. Cancer medicine. 2018; 7(4):1141-1150.
4.Lin J, Peng J, Zhao Y, Luo B, Zhao Y, Deng Y, Sui Q, Gao Y, Zeng Z, Lu Z and Pan Z. Early recurrence in patients undergoing curative resection of colorectal liver oligometastases: identification of its clinical characteristics, risk factors, and prognosis. Journal of cancer research and clinical oncology. 2018; 144(2):359-369.
5.Zhang RX, Lin JZ, Lei J, Chen G, Li LR, Lu ZH, Ding PR, Huang JQ, Kong LH, Wang FL, Li C, Jiang W, Ke CF, Zhou WH, Fan WH, Liu Q, et al. Safety of intraoperative chemotherapy with 5-FU for colorectal cancer patients receiving curative resection: a randomized, multicenter, prospective, phase III IOCCRC trial (IOCCRC). Journal of cancer research and clinical oncology. 2017; 143(12):2581-2593.
6.Sui Q, Lin J, Peng J, Zhao Y, Deng Y and Pan Z. Local surgical excision versus endoscopic resection for rectal carcinoid: A meta-analysis. Journal of Cancer. 2017; 8(19):3969-3974.
7.Peng J, Lin J, Zeng Z, Wu X, Chen G, Li L, Lu Z, Ding P, Wan D and Pan Z. Addition of oxaliplatin to capecitabine-based preoperative chemoradiotherapy for locally advanced rectal cancer: Long-term outcome of a phase II study. Oncology letters. 2017; 14(4):4543-4550.
8.Peng J, Lin J, Qiu M, Zhao Y, Deng Y, Shao J, Ding P, Zhang H, Wan D, Lu Z and Pan Z. Oncogene mutation profile predicts tumor regression and survival in locally advanced rectal cancer patients treated with preoperative chemoradiotherapy and radical surgery. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 2017; 39(7):1010428317709638.
9.Deng YX, Lin JZ, Peng JH, Zhao YJ, Sui QQ, Wu XJ, Lu ZH, Gao YH, Zeng ZF and Pan ZZ. Lymphocyte-to-monocyte ratio before chemoradiotherapy represents a prognostic predictor for locally advanced rectal cancer. OncoTargets and therapy. 2017; 10:5575-5583.
10.Peng J, Lin J, Qiu M, Wu X, Lu Z, Chen G, Li L, Ding P, Gao Y, Zeng Z, Zhang H, Wan D and Pan Z. Clinical factors of post-chemoradiotherapy as valuable indicators for pathological complete response in locally advanced rectal cancer. Clinics. 2016; 71(8):449-454.
11.Lin JZ, Peng JH, Qdaisat A, Lu ZH, Wu XJ, Chen G, Ding PR, Li LR, Gao YH, Zeng ZF, Wan DS and Pan ZZ. Preoperative chemoradiotherapy creates an opportunity to perform sphincter preserving resection for low-lying locally advanced rectal cancer based on an oncologic outcome study. Oncotarget. 2016; 7(35):57317-57326.
12.Lin J, Peng J, Qdaisat A, Li L, Chen G, Lu Z, Wu X, Gao Y, Zeng Z, Ding P and Pan Z. Severe weight loss during preoperative chemoradiotherapy compromises survival outcome for patients with locally advanced rectal cancer. Journal of cancer research and clinical oncology. 2016; 142(12):2551-2560.
13.Lin J, Qiu M, Xu R and Dobs AS. Comparison of survival and clinicopathologic features in colorectal cancer among African American, Caucasian, and Chinese patients treated in the United States: Results from the surveillance epidemiology and end results (SEER) database. Oncotarget. 2015; 6(32):33935-33943.
14.Gao YH, Lin JZ, An X, Luo JL, Cai MY, Cai PQ, Kong LH, Liu GC, Tang JH, Chen G, Pan ZZ and Ding PR. Neoadjuvant sandwich treatment with oxaliplatin and capecitabine administered prior to, concurrently with, and following radiation therapy in locally advanced rectal cancer: a prospective phase 2 trial. International journal of radiation oncology, biology, physics. 2014; 90(5):1153-1160.
15.Lin JZ, Zeng ZF, Wu XJ, Wan DS, Chen G, Li LR, Lu ZH, Ding PR and Pan ZZ. Phase II study of pre-operative radiotherapy with capecitabine and oxaliplatin for rectal cancer and carcinoembryonic antigen as a predictor of pathological tumour response. The Journal of international medical research. 2010; 38(2):645-654.
二、承担和参与的科研课题
1、CSN6调控上皮间质转化促进结直肠癌肝转移的分子机制研究,广东省自然科学基金博士科研启动项目,2017A030310204,10万元,2017/05—2020/05,主持
2、MEK在RAS突变型结肠癌对西妥昔单抗耐药中的作用及分子机制研究,广东省医学科学技术研究基金,A2017545,0.5万元,2017/07—2019/06,主持
3、MDM2/p53小分子抑制剂APG-115对肠癌的抗肿瘤作用及其机制研究,国家自然科学基金面上项目,81772587,2018/01-2021/12,52万元,参与
4、二十二碳六烯酸下调电压门控钠通道SCN5A阻断上皮间质转化抑制结直肠癌侵袭转移的分子机制,国家自然科学基金面上项目,81772595,45万元,2018/01-2021/12, 参与
5、结直肠癌遗传性家系队列研究,国家重点研发计划课题,2017YFC0908202,2017/07-2020/12,192万元,参与
6、RAC1/RAC1b活性蛋白比率预测不同BRAF突变状态的II期结直肠癌预后的价值和机制,广东省自然科学基金面上项目,2015A030313056,10万元,2015/08—2018/08,参与
7、结直肠癌手术视频云的关键技术应用开发,广东省科技计划项目面上项目,2013B090800047,50万元,2015/01—2016/12,参与
8、镍钛记忆合金加压吻合环在直肠癌手术肠道重建的临床研究,广东省科技计划项目面上项目,2012B031800072,3万元,2013/01—2015/12,参与
9、ERβ受体在结肠癌肝转移个体化内分泌治疗中的作用和意义,广东省自然科学基金面上项目,S2012010011132,3万元,2012/10—2014/10,参与
10、靶向雌激素受体beta对结肠癌肝转移的影响、机制和临床意义,国家自然科学基金青年基金,81101861,24万元,2012/01—2014/12,参与
11、EZH2 基因诱导结肠癌细胞上皮-间质转化促进转移的机制研究,国家自然科学基金青年基金,81101591,22万元,2012/01—2013/12,参与
12、靶向抑制调节性T细胞逆转直肠癌放化疗抗拒的研究,广东省省自然科学基金面上项目,9151008901000066,5万元,2009/10—2011/09,参与
13、蛋白质组学筛选直肠癌干细胞放化疗敏感性预测因子的研究,广东省科技计划项目面上项目,2008B030301119,4万元,2009/01—2011/12,参与
三、专业著作:
1、《中国结直肠癌肝转移MDT临床实践共识》编委,2016,人民卫生出版社
2、《社区肿瘤防治丛书》编委,2009,广东科技出版社
3、《中国肿瘤医师临床实践指南丛书――结直肠癌》编委,2008,北京大学医学出版社
4、《造口康复治疗-理论与实践》编委,2006,中国医药科技出版社
更新日期:2018年7月13日