曾木圣

曾木圣研究员，中国科学院院士，现任中山医学院院长、中山大学肿瘤防治中心副主任/副院长和“国际EB病毒及相关疾病研究协会”主席，主要从事EB病毒致癌机制与干预研究。

代表性论文

1. A broadly protective antibody targeting gammaherpesvirus gB. Cong Sun^#, Chu Xie^#, Bing-Zhen Cheng^#, Zi-Ying Jiang, Pei-Huang Wu, Xin-Yan Fang, Peng-Lin Li, Xian-Shu Tian, Hang Zhou, Yan-Lin Yang, Jing Wang, Sen-Fang Sui, Zheng Liu*, Mu-Sheng Zeng*. Nature.  2026 Feb 2. doi: 10.1038/s41586-026-10192-5.
2. R9AP is a common receptor for EBV infection in epithelial cells and B cells. Yan Li ^#, Hua Zhang ^#, Cong Sun ^#, Xiao-Dong Dong ^#, Chu Xie, Yuan-Tao Liu, Ruo-Bin Lin, Xiang-Wei Kong, Zhu-Long Hu, Xiao-Yan Ma, Dan-Ling Dai, Qian-Ying Zhu, Yu-Chun Li, Ying Li, Shang-Xin Liu, Li Yuan, Peng-Hui Zhou, Song Gao, Ya-Ping Tang, Jin-Ying Yang, Ping Han, Andrew T McGuire, Bo Zhao, Jin-Xin Bei, Erle Robertson, Yi-Xin Zeng, Qian Zhong*, Mu-Sheng Zeng*. Nature. 2025 Aug;644(8075):205-213. doi: 10.1038/s41586-025-09166-w. Epub 2025 Jun 18.
3. Desmocollin 2 is a dominant entry receptor for Epstein-Barr virus infection of epithelial cells. Hua Zhang ^#*, Yu-Chun Li ^#, De Pang ^#, Chu Xie ^#, Ting Zhang, Ying Li, Yan Li, Zi-Ying Jiang, Guo-Long Bu, Meng-Meng Liu, Ying-Rou Chen, Han-Xiao Fei, Ruo-Bin Lin, Pei-Huang Wu, Wen-Ting Du, Ge-Xin Zhao, Yi-Ling Luo, Ping Han, Qian Zhong, Cong Sun*, Mu-Sheng Zeng*. Nature Microbiology. 2025 Jul 25. doi: 10.1038/s41564-025-02067-8.
4. A large-scale population-based study reveals that gp42-IgG antibody is protective against Epstein-Barr virus-associated nasopharyngeal carcinoma. Xiang-Wei Kong^#, Guo-Long Bu^#, Hua Chen^#, Yu-Hua Huang^#, Zhiwei Liu, Yin-Feng Kang, Yan-Cheng Li, Xia Yu, Biao-Hua Wu, Zi-Qian Li, Xin-Chun Chen, Shang-Hang Xie, Dong-Feng Lin, Tong Li, Shu-Mei Yan, Run-Kun Han, Nan Huang, Qian-Yu Wang, Yan Li, Ao Zhang, Qian Zhong, Xiao-Ming Huang, Weimin Ye, Ming-Fang Ji*, Yong-Lin Cai*, Su-Mei Cao*, Mu-Sheng Zeng*. Journal of Clinical Investigation. 2024 Nov 26:e180216. doi: 10.1172/JCI180216.
5. A gB nanoparticle vaccine elicits a protective neutralizing antibody response against EBV. Cong Sun^#, Yin-Feng Kang^#, Xin-Yan Fang^#, Yi-Na Liu^#, Guo-Long Bu, Ao-Jie Wang, Yan Li, Qian-Ying Zhu, Hua Zhang, Chu Xie, Xiang-Wei Kong, Yong-Jian Peng, Wen-Jie Lin, Ling Zhou, Xin-Chun Chen, Zheng-Zhou Lu, Hui-Qin Xu, Dong-Chun Hong, Xiao Zhang, Ling Zhong, Guo-Kai Feng, Yi-Xin Zeng, Miao Xu, Qian Zhong*, Zheng Liu*, Mu-Sheng Zeng*. Cell Host & Microbe. 2023 Nov 8;31(11):1882-1897.e10. doi: 10.1016/j.chom.2023.09.011.

Email: zengmsh@sysucc.org.cn通讯地址：广州市东风东路651号，中山大学肿瘤防治中心实验研究部，邮编510060

更新日期：2026年8月6日