博士后合作导师

骆卉妍

内科主任医师，主要从事消化道肿瘤的化学治疗和靶向治疗，以及肿瘤耐药和克服耐药的转化性研究、液体活检在消化系统中的应用、消化系统肿瘤人工智能诊疗决策系统的研发等。作为主要研究人员主持或参与国家重点研发项目、国家科国家自然科学基金重点项目、国家自然科学基金面上项目、国家自然科学基金青年项目、广东省自然科学基金项目、广州市科技计划项目等多项科研课题，参与和完成100余项国际、国内多中心I、II、III期临床研究。在国内外期刊发表文章70余篇，并以第一/共一作者在《JAMA》、《Nature materials》、《Lancet Oncology》、《Science Translational Medicine》、《Annual of oncology 》、《PNAS》、《Clin Cancer Res》等国际顶级杂志上发表SCI论文20余篇，其中两篇被美国NCCN指南收录。申请专利9项，授权3项。作为主要参与人，获得国家科技进步二等奖一项，省部级一等奖4项项。目前任中国抗癌协会胃癌专业委员会青委副主任委员、广东省抗癌协会肿瘤靶向治疗专业委员会常委兼秘书、广东省医学教育协会肿瘤学专业委员会副主任委员。

代表性文章、成果： 

  1. Luo H, Lu J, Bai Y, et.al. ESCORT-1st Investigators. Effect of Camrelizumab vs Placebo Added to Chemotherapy on Survival and Progression-Free Survival in Patients With Advanced or Metastatic Esophageal Squamous Cell Carcinoma: The ESCORT-1st Randomized Clinical Trial. JAMA. 2021 Sep 14;326(10):916-925. doi: 10.1001/jama.2021.12836. (IF 56.3)
  2. Huiyan Luo, Guoliang Xu, Chaofeng Li, et al. Real-time artificial intelligence for detection of upper gastrointestinal cancer by endoscopy: a multicentre, case-control, diagnostic study. The Lancet Oncology, 20(12), December 2019, 1645-1654 (IF 35.4)
  3. Huiyan Luo, Qi Zhao, Wei Wei, et al. Circulating tumor DNA methylation profiles enable early diagnosis, prognosis prediction, and screening for colorectal cancer. Science Translational Medicine 01 Jan 2020:Vol.12, Issue 524, eaax7533 (IF 17.2)
  4. Peishan Hu, Ting Li, Jinfei Lin, Miao-Zhen Qiu, De-Shen Wang, Ze-Xian Liu, Zhan-Hong Chen, Xiao-Long Zhang, Qi Zhao, Lu-Ping Yang, Yan-Xing Chen, Yun-Xin Lu, Qi-Nian Wu, Heng-Ying Pu, Zhao-Lei Zeng, Dan Xie, Huai-Qiang Ju#, Hui-Yan Luo#, Rui-hua Xu#. VDR-SOX2 Signaling Promotes Colorectal Cancer Stemness and Malignancy in an Acidic Microenvironment. Signal Transduction and Targeted Therapy 2020 (IF 38.4).
  5. Luo XJ, He MM, Liu J, Zheng JB, Wu QN, Chen YX, Meng Q, Luo KJ, Chen DL, Xu RH, Zeng ZL, Liu ZX#, Luo HY#. LncRNA TMPO-AS1 promotes esophageal squamous cell carcinoma progression by forming biomolecular condensates with FUS and p300 to regulate TMPO transcription. Exp Mol Med. 2022 Jun;54(6):834-847. (IF12.15)
  6. Zhang Z, Wu HX, Lin WH, Wang ZX, Yang LP, Zeng ZL, Luo HY#. EPHA7 mutation as a predictive biomarker for immune checkpoint inhibitors in multiple cancers. BMC Med. 2021 Feb 2;19(1):26. (IF11.15)