博士后合作导师

宋远斌

宋远斌，医学博士，青年研究员，博士研究生导师

中山大学肿瘤医院血液肿瘤科，华南肿瘤学国家重点实验室独立PI，国家高层次人才青年项目获得者，中山大学“百人计划”引进人才。

广东省医学会血液病学分会青年委员、广东省精准医学应用学会单细胞科技分会委员、中国生物医学工程学会干细胞分会委员、美国血液协会会员、Chinese Medicine 青年编委，Frontier in Pharmacology/ Frontier in Genetics审稿编辑 。

   南方医科大学临床医学八年制博士毕业，2013-2020年于美国耶鲁大学医学院肿瘤中心血液肿瘤任博士后、助理研究员。研究工作主要聚焦于骨髓增生异常综合征、急性髓系白血病人源化小鼠模型的建立及靶向治疗的临床前研究，以第一作者（含共同）在Science、Leukemia、Nature Communications、Immunity等发表多篇论文，主持国家自然科学基金青年基金1项、面上基金1项。  

基金：

2019年国家自然科学基金青年基金“异柠檬酸脱氢酶突变体特异性抑制剂靶向消除骨髓增生异常综合征干细胞的有效性研究”（81800122），排名第一，为项目负责人。

2021年国家自然科学基金面上项目“多腺苷二磷酸多聚酶抑制剂靶向消除异柠檬酸脱氢酶突变型骨髓增生异常综合征及急性髓系白血病干细胞的有效性研究”（82170137），排名第一，为项目负责人。

近5年文章：

  1. Yuanbin Song, Liang Shan, Rana Gbyli, Wei Liu, Till Strowig, Amisha Patel, Xiaoying Fu, Xiaman Wang, Mina Xu, Yimeng Gao, Ashley Qin, Emanuela M Bruscia, Toma Tebaldi, Giulia Biancon, Padmavathi Mamillapalli, David Urbonas, Elizabeth Eynon, David Gonzales, Jie Chen, Diane S. Krause, Jonathan Alderman, Stephanie Halene, Richard Flavell. Combined liver-cytokine humanization comes to the rescue of circulating human RBC. Science, 2021 Mar 5; 371(6533):1019-1025.
  2. Yuanbin Song, Anthony Rongvaux, Ashley Taylor, Tingting Jiang, Toma Tebaldi, Kunthavai Balasubramanian, Arun Bagale, Yunus Terzi, Rana Gbyli, Xiaman Wang, Xiaoying Fu, Yimeng Gao, Jun Zhao, Nikolai A. Podoltsev, Mina Xu, Natalia Neparidze, Ellice Wong, Richard Torres, Emanuela M Bruscia, Yuval Kluger, Markus G Manz, Richard Flavell, Stephanie Halene. A Highly Efficient and Faithful MDS Patient-Derived Xenotransplantation Model for Pre-Clinical Studies. Nature Comm, 2019, 10 (1): 366.
  3. Yimeng Gao, Radovan Vasic, Yuanbin Song（Co first author）, Rhea Teng, Rana Gbyli, Giulia Biancon, Raman Nelakanti, Anastasia Ardasheva, Xiaoying Fu, Xiaman Wang, Burak Dura, Veronica Lee, Gabriella Viero, Rong Fan, Andrew Xiao, Richard A. Flavell, Hua-Bing Li, Toma Tebaldi, Stephanie Halene. Loss of METTL3 Mediated m6A RNA Modification Results in Double-Stranded RNA Induced Antiviral Innate Immune Response and Hematopoietic Failure. Immunity. 2020, Jun 16;52(6):1007-1021.
  4. Yuanbin Song, Rana Gbyli, Xiaoying Fu, Stephanie Halene. Functional Analysis of Human Hematopoietic Stem Cells In Vivo in Humanized Mice. Methods Mol Biol. 2020; 2097: 273-289. 
  5. Rana Gbyli, Yuanbin Song (Co first author & Corresponding author), Wei Liu, Yimeng Gao, Giulia Biancon, Namrata S Chandhok, Xiaman Wang, Xiaoying Fu, Amisha Patel, Ranjini Sundaram, Toma Tebaldi, Padmavathi Mamillapalli, Amer M Zeidan, Richard A. Flavell, Thomas Prebet, Ranjit S. Bindra, Stephanie Halene.In vivo anti-tumor effect of PARP inhibition in IDH1/2 mutant MDS/AML resistant to targeted inhibitors of mutant IDH1/2. Leukemia (2022). https://doi.org/10.1038/s41375-022-01536-x
  6. Liu, Haiyan, Ziping Li, Fei Qiu, Chunjie Li, Xiaojing Lin, Yingyi He, Maoxiang Qian, Yuanbin Song (Corresponding author), Hui Zhang. Association between Nr3c1 Mutations and Glucocorticoid Resistance in Children with Acute Lymphoblastic Leukemia. Frontiers in Pharmacology 2021, 12(562).
  7. Rana Gbyli, Yuanbin Song（Co first author）, Stephanie Halene. Humanized mice as preclinical models for myeloid malignancies. Biochemical Pharmacology. 2020; Apr; 174:113794.