赖仁纯
赖仁纯，男，46岁，医学博士，主任医师，硕士生导师。
研究方向：麻醉、疼痛与肿瘤
主持项目情况：2022年广东省自然科学基金《DRG神经元Thbs1通过PEKR-EIF2a信号通路调控ATF4介导的TRPM3转位细胞膜参与热痛敏的机制研究》；2022年广州市科技项计划基础与应用基础研究项目《DRG神经元TLR-MyD88信号通路调控ATF4介导TRPM3转位细胞膜参与热痛敏的机制研究》
近五年代表性研究成果：
1 Lai RC, Shan WR, Zhou D, Zeng XQ, Zuo K, Pan DF, Zeng WA, Zuo ZY. Sevoflurane promotes migration, invasion, and colony-forming ability of human glioblastoma cells possibly via increasing the expression of cell surface protein 44. Acta Pharmacol Sin. 2019 Nov;40(11):1424-1435.
2 Zhang XL, Lai RC, Chen ZH, Zhong XX, Cao XY, Zhang X, Xiao YB, Wang JC, Liu XG, Xie MX. Foxo1 selectively regulates static mechanical pain by interacting with Nav1.7. Pain. 2021 Feb 1;162(2):490-502. （并列第一）
3 Lai J, Situ D, Xie M, Yu P, Wang J, Long H, Lai R. Continuous Paravertebral Analgesia versus Continuous Epidural Analgesia after Video-Assisted Thoracoscopic Lobectomy for Lung Cancer: A Randomized Controlled Trial. Ann Thorac Cardiovasc Surg. 2021 Oct 20;27(5):297-303.
4 Huang XW, Wang XD, Lai JL, Lu YL, Deng K, Lai RC. Effects of Anesthetic Technique on Postoperative Pulmonary Metastasis in Patients Undergoing Laryngectomy. Cancer Manag Res. 2020 Jul 7;12:5515-5525.
5 Lai G, Guo N, Jiang Y, Lai J, Li Y, Lai R. Duration of one-lung ventilation as a risk factor for postoperative pulmonary complications after McKeown esophagectomy. Tumori. 2020 Feb;106(1):47-54.
6 Lu X, Yu P, Ou C, Wang J, Zhou Z, Lai R. The Postoperative Analgesic Effect of Ultrasound-Guided Bilateral Transversus Abdominis Plane Combined with Rectus Sheath Blocks in Laparoscopic Hepatectomy: A Randomized Controlled Study. Ther Clin Risk Manag. 2020 Sep 18;16:881-888.
7 Lai R, Luo Q, Lai J, Lu X, Xu M. Ultrasound-guided quadratus lumborum block for perioperative analgesia in robot-assisted partial nephrectomy: a randomized controlled trial. Trials. 2021 Nov 24;22(1):840.
8 Xie MX, Cao XY, Zeng WA, Lai RC, Guo L, Wang JC, Xiao YB, Zhang X, Chen D, Liu XG, Zhang XL. ATF4 selectively regulates heat nociception and contributes to kinesin-mediated TRPM3 trafficking. Nat Commun. 2021 Mar 3;12(1):1401. （并列第一）
9 Li W, Yan Y, Zheng Z, Zhu Q, Long Q, Sui S, Luo M, Chen M, Li Y, Hua Y, Deng W, Lai R, Li L. Targeting the NCOA3-SP1-TERT axis for tumor growth in hepatocellular carcinoma. Cell Death Dis. 2020 Nov 25;11(11):1011. （并列通讯）
10 Yang MZ, Lai RC, Abbas AE, Park BJ, Li JB, Yang J, Wu JC, Wang G, Yang HX. Learning curve of robotic portal lobectomy for pulmonary neoplasms: A prospective observational study. Thorac Cancer. 2021 May;12(9):1431-1440. （并列第一）
11 Wang H, Shao R, Lu S, Bai S, Fu B, Lai R, Lu Y. Integrative Analysis of a Pyroptosis-Related Signature of Clinical and Biological Value in Multiple Myeloma. Front Oncol. 2022 Feb 28;12:845074. （并列通讯）
12 Pan YX, Wang JC, Lu XY, Chen JB, He W, Chen JC, Wang XH, Fu YZ, Xu L, Zhang YJ, Chen MS, Lai RC, Zhou ZG. Intention to control low central venous pressure reduced blood loss during laparoscopic hepatectomy: A double-blind randomized clinical trial. Surgery. 2020 Jun;167(6):933-941. （并列通讯）
